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The First Few Weeks Many users notice headaches within the first month of treatment

While mild discomfort can happen with appetite changes, sharp or increasing pain might mean you have pancreatitis , which is a rare but serious issue related to GLP-1 medications

People with type 2 diabetes may also see their blood sugar levels go up again

Oral semaglutide 14 mg showed similar weight reductions to once-daily liraglutide 1.8 mg when added to metformin an SGLT2 (sodium-glucose co-transporter-2) inhibitor

This allows more water absorption from stool in the colon, resulting in harder, more difficult-to-pass stools