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Upon ligand binding, activation of downstream signalling pathways (e.g., nuclear factor kappa-B [NF-B] and mitogen-activated protein kinase [MAPK]) leads to the transcription of genes encoding pro-inflammatory cytokines and chemokines such as tumor necrosis factor (TNF)-, interleukin (IL)-1, IL-8, IL-18 and interferons (IFN)

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Comorbidity Interactions : Older participants with multiple health conditions may experience more complex interaction patterns with aod 9604 peptides