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used a neutralizing antibody of ANGPTL4 in both humanized mice and nonhuman primates, which resulted in severe side effects and systemic metabolic abnormalities (Srivastava et al., 2024)

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However, the intervention did lead to improved glycaemic control, blood pressure and lipid levels, as well as a higher rate of achieving and maintaining clinically significant weight loss

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Peptides are naturally occurring short chains of amino acids, acting as the building blocks for proteins in the body