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In cases where weight data were not directly reported, estimates were extracted from graphical representations using WebPlotDigitizer (v4.5), to extract numerical data points from graphical figures by two independent reviewers, with mean values cross-verified to minimize digitization error ( 90%), while semaglutide had much lower heterogeneity, indicating consistency across those studies

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The company markets its GLP-1 stack as a natural support supplement, but it does not contain semaglutide, tirzepatide, or any other prescription GLP-1 ingredient