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SETD8 potentiates constitutive ERK1/2 activation via epigenetically silencing DUSP10 expression in pancreatic cancer

Approximately 50 mg fresh red and white gastrocnemius muscle and liver were immediately placed into ice-cold modified sucrose EDTA medium (SET) on ice containing 250 mmol/l sucrose, 1 mmol/l EDTA and 10 mmol/l TrisHCl, pH 7.4

1528-P: hypothalamic SEL1L-HRD1 ER-associated degradation is indispensable for leptin signaling in diet-induced obesity by degrading misfolded leptin receptor