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This could help explain individual differences among humans in responsiveness to these drugs, including some well-known sex differences

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Strategies that support microbial diversity, including probiotic supplementation (particularly Lactobacillus and Bifidobacterium strains studied in atopic conditions), prebiotic fiber intake, and avoidance of unnecessary antibiotics, create a more favorable environment for peptide interventions

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Whether the animals consumed a high-fat diet or not, tirzepatide administration significantly reduced tumor weight