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The primary outcome is simple but meaningful: How many heavy drinking days per week they have at the end of the study compared to when they started. Secondary outcomes include changes in WHO risk categories and levels of phosphatidylethanol, a blood biomarker for alcohol use

Stopping Semaglutide Before Colonoscopy Whether patients should stop semaglutide before a colonoscopy remains a key question

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Metformin may be weight-neutral or cause modest weight loss in some people, but it is not usually chosen as a primary weight-loss medicine

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