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Additionally, a previous in vivo study revealed that GLP-1(736) attenuated 1-42-induced neuronal cell death in murine hippocampal HT22 cells and improved pathological changes [53]

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One peptide, VMP3, bound VEGFR2 with 1.60 nM affinity at a structurally distinct site, activated the full downstream signaling cascade in endothelial cells, and promoted functional neovascularization in both ex vivo and in vivo models

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