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The presenting author(s) of the original presentation had no involvement in the creation of this content

In addition, information on disease severity, extent of skin involvement, and treatment response was unavailable, precluding analyses of doseresponse relationships or severity-specific outcomes

Discussion In recent years, numerous studies recognized the TMAO as an enhancer of cardiovascular risk via atherosclerotic lesion development [5,6,7]

It was designed to treat obesity by targeting peripheral receptors, but some researchers believe it might actually exert its effects through CB1 receptors in the central nervous system 15

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