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The effect of semaglutide on hsCRP was partially mediated via reductions in HbA 1c and BW, which may therefore be involved in a potential anti-inflammatory effect of semaglutide

Ketoconazole can cause elevated plasma concentrations of selected drugs metabolized via CYP3A4 which may prolong the QT interval, sometimes resulting in life-threatening ventricular arrhythmias such as torsade de pointes