Additionally, the NNMT substrate nicotinamide 12 is metabolized by the microbiome 56,57 , and thus NNMTi may modulate substrate availability, potentially influencing microbial metabolic capacity to drive the NNMTi-mediated weight loss
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Disclosure of interest: None Poster session I - DIAGNOSIS / ETIOLOGY 04.00 - DIAGNOSIS / ETIOLOGY - 04.09 - SEX, GENDER AND STROKE P366 - ESOC25-2375 IMPACT OF GENDER AND ANTICOAGULATION ON STROKE OUTCOMES AMONG PATIENTS TREATED FOR LARGE VESSEL OCCLUTION STROKE Benedikte Lea Nygaard 1 , Martin Kurz 1 , Soffien Ajmi 1 , Camilla Jacqueline Hansine Normand 2 1 Department of Neurology, Stavanger University Hospital, Stavanger, Norway, 2 Division of Internal Medicine, Stavanger University Hospital, Stavanger, Norway Background and Aims: Gender and age disparities in stroke outcomes and anticoagulation management may affect recovery following large vessel occlusion (LVO)
Vitamin C plays a key role in immune function, collagen production, and protection against oxidative stress