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Joint and Muscle Aching: Systemic inflammation and the accumulation of lactic acid and other metabolic waste products in the tissues cause widespread pain

44 Upon activation, the D 2 -like receptors will stimulate a variety of processes including acute signaling events (inhibition of adenylyl cyclase, stimulation of K + channels, inhibition of Ca 2+ channels, stimulation of arachidonic acid release) as well as longer-term events (MAP kinase and -arrestin-2/Akt/GSK-3 signaling, and mitogenesis)

(2001) Journal of Clinical Pharmacology n=34 Pharmacokinetic study establishing AOD 9604 peak plasma levels, elimination half-life, and subcutaneous bioavailability

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This does not mean the treatment failed or that you are doing something wrong