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Molecular mechanisms of oxidative stress in stroke and cancer
Isoquercetin can significantly alleviate retinal damage in mice with DR, and in vitro studies have confirmed that its protective effect is mediated by inhibiting the p53 signaling pathway (227)
Options include Chimeric antigen receptor T-cell therapy (CAR-Tcell), a form of adoptive T-cell transfer, cancer vaccines, monoclonal/polyclonal or therapeutic antibodies, oncolytic virus therapies, immune-system modulators, cytokine therapies, and immune checkpoint inhibitors which are negative regulators of T cells [14], as shown in Fig
We attempted to minimize the effects of potential confounders through for example not including patients with comorbid conditions