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Superoxide dismutase 1 (SOD1) is also dependent on copper and likewise would see a decline in activity, supported by a study observing A directly interacting with SOD1 and decreasing enzymatic activity (Yoon et al., 2009)

Statistics All results were represented as means standard error of the mean (SEM)

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However, recent research has uncovered a broader range of pathophysiologic mechanisms contributing to disease progression [144,145,146,147]