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In deeply anaesthetised rats (placed in ventral position) the tail was transected with a surgical scalpel 3 cm from the tip (and submerged into a tube with 15 ml of saline at room temperature in vertical position) and the duration and amount of bleeding were measured to evaluate the hemostatic effect of the agents or saline administration

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Increased VEGF expression and neovascularization in irradiated wounds Improved wound closure rates compared to control in compromised tissue Demonstrates efficacy even in radiation-impaired healing environments Comprehensive review of GHK and GHK-Cu: stimulation of collagen, elastin, and connective tissue accumulation