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2.1 Potential involvement of exerkines in exercise-mediated alleviation of atherosclerosis Exercise can influence the levels of various exerkines, such as tumor necrosis factor (TNF), leptin, resistin, adiponectin, irisin, glucagon-like peptide-1 (GLP-1), fibroblast growth factor 21 (FGF21), among others

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TB-500's cell migration properties mean that fibroblasts, the cells responsible for collagen synthesis, can move more efficiently to areas where they're needed