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Despite some controversies, such as drug concentration and timing, inconsistent conclusions due to different definitional parameters, and insufficient research on the mechanism of influence, these findings can help clinicians choose the most appropriate treatment plan and clinical follow-up

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Resveratrol is the most well-known SIRT1 activator

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Modulation of glucocorticoid inhibitory action on human lymphocyte mitogenesis: dependence on mitogen concentration and T-cell maturity