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Effect of naltrexone plus bupropion on weight loss in overweight and obese adults (COR-I): a multicentre, randomised, double-blind, placebo-controlled, phase 3 trial The COR-I study found that a combination of sustained-release naltrexone and bupropion significantly reduced bodyweight in obese individuals over 56 weeks, with 48% achieving at least a 5% weight loss, while nausea was the most common side effect
Dr Carreon uses the latest technology to ensure precision, safety, and long-lasting results tailored to each clients unique body goals
Machado agrees
This is critical for treating weight loss and metabolic disease, where success depends not only on the target but how its delivered
The findings are relevant for long Covid, which shares many symptoms with MCAS
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