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Integration of allosteric regulation of phosphofructokinase-1 varies among its isoforms, and it is shaped to fit the needs of neoplasia in maintaining phosphofructokinase-1 activity to a high level, especially in view of ample derivation of citrate from other sources, such as reductive carboxylation of glutamine 98

Ang II also promotes the presence of superoxide species in a biological system, which gone unchecked, results in oxidative stress

The increase in the production of glutathione and other detoxification enzymes may result in the liberation of these from the body resulting in symptoms

There is no meaningful difference between these terms in practice