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Kidney Disease: Patients with kidney disease should use B12 injections with caution, as the kidneys are involved in metabolizing B12

NNMT inhibition increases intracellular concentrations of NAD + and SAM in differentiated adipocytes Figure 3A outlines the major elements of the mammalian NAD+ salvage pathway using NA as the starting substrate.[27] Since the NNMT inhibitor 5-amino-1MQ significantly reduced intracellular 1-MNA concentrations (Figures 2B and 2C), we hypothesized that NNMT inhibition in adipocytes would increase intracellular concentrations of the co-substrates NA and SAM and shunt more NA into the NAD + salvage cycle

They can then change the dose if needed

Where can I find additional resources for 5-Amino-1MQ research

Eating these fortified foods can be an effective way to boost B12 levels