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M: protein marker, Lane 1: unbound eluate from the Ni-NTA affinity chromatography column using crude protein extracts from pEASY-E2-6mGLP-1/transetta (DE3) cells induced by IPTG, Lane 2: bound eluate, Lane 3: final purified 6mGLP-1

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Nature 546, 248253

This study investigated whether GE2 improves cognition, reduces neuroinflammation, and enhances synaptic plasticity in the hippocampus of middle-aged male and female rats fed a standard (SD) or high-fat, high-sugar (Western) diet (WD)