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Preclinical studies indicate that senescent cell burden is low in young rodents and increases with chronological age in several tissues (33, 34)

Moreover, some Chinese scholars have found that dysfunction of the mTOR signaling pathway is closely related to tumor formation, and mTOR protein is highly expressed in glioma, suggesting that abnormal mTOR signaling may be an important pathogenesis of glioma

Gudenkauf, B., Goetsch, M

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The association of the variant GPX4 genotypes with the increased risk of CS in hypertensives remained statistically significant (OR=2.18, 95%CI 1.463.27, P adj =0.0015) after adjusting for confounding variables such as sex, BMI, blood pressure and antihypertensive-medication use