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However, they also release neurotrophic factors in support of neurons 62 and they contribute to neuroprotection against glutamate excitotoxicity 63 and oxidative stress 64,65

The area postrema (AP) is a circumventricular organ of the hindbrain with a leaky blood-brain barrier, previously identified as a region associated with nausea and vomiting [100,101]

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Lastly, GLP- 1 receptor agonists'impact on weight may help improve blood glucose regulation and insulin sensitivity simultaneously

A 2026 review in Anais Brasileiros de Dermatologia found most local reactions are transient and resolve without dose adjustment