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Betteridge, D

Thanks for any thoughts, Kelly Since hormetic compounds display a U-shaped biphasic dose-response curve, meaning that at low/optimal doses they improve health and have a reverse tolerance effect (get more powerful with frequent use), but at high doses have detrimental effects, Im wondering whether or not many of the supplements on the market containing high doses of these compounds (Like EGCG, Curcumin, and Resveratrol) are dangerous

10.1016/j.bioorg.2017.10.006 90 Sharifi-RigiA.HeidarianE.AminiS

doi: 10.1038/nm.2609 24 ArenaSBellosilloBSiravegnaGMartnezACanadasILazzariLet al

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