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Our study did not specifically investigate the reasons for discontinuation, so further research would be needed to answer this question definitively. Bartelt added that health care providers should discuss the potential for weight regain after discontinuation with their patients and reiterate the importance of incorporating other weight management strategies, such as diet and exercise. Future research could focus on understanding the reasons for weight regain after discontinuation of these drugs and explore the long-term effects these drugs have on weight management and other side effects, she said

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The risk-benefit calculation is fundamentally different from taking an expired ibuprofen

Fras JP, et al

Read our complete guide on your first week on semaglutide for day-by-day guidance on what to expect and how to eat during those initial days