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After 14 days of tumor formation, the nude mice bearing tumors were randomly divided into four groups and intravesically treated with 500 L si-PGC-1 LNP, equimolar dose of LNP, si-PGC-1 alone, or PBS solution

GLUTATHIONE, a naturally occurring protein, is called a peptide

Macronutrient ratios started at 2.5:1 for the first month (198 g fat, 56 g protein, 22 g net carbs) to prioritize ketone production and shifted to 2:1 (186 g fat, 70 g protein, 20 g net carbs) during treatment, both classified as modified ketogenic diets

The association of hypercortisolemia with mortality in critically ill neonates was confirmed in a separate, larger study (320)

doi: 10.2337/db11-1300 37 CampbellJMBellmanSMStephensonMDLisyK