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Novo also reported in early 2026 that CagriSema showed superior HbA1c reduction and weight loss vs semaglutide in a Phase 3 diabetes program (REIMAGINE 2)

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Certain drugs are associated with weight gain, including some antipsychotics (olanzapine, quetiapine), mood stabilisers (sodium valproate, lithium), antidepressants (mirtazapine, some tricyclics), corticosteroids, insulin, sulfonylureas, and beta-blockers