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Inhibition of PPAR leads to serum acylcarnitine accumulation [190], whereas hepatic PPAR activation induced by energy deprivation or fibrates is associated with an increase in the carnitine concentration and a decrease in serum acylcarnitine accumulation [191, 192]

Weight-based dosing provides a more individualized approach than flat-dose recommendations

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Treatments result depends on individual skin type, the underlying cause of pigmentation, and the laser technology used