Neurons innervating the striatum, including dopaminergic neurons from the SNcVTA regions, take up AA, which, in low-TH-expressing cells, the phenotype can switch to a dopaminergic one through TH synthesis
Some individuals may experience mild digestive discomfort initially
Effects of total bilirubin, direct bilirubin, free radical levels, total antioxidant status, glutathione peroxidase, glutathione reductase and the lag time for low-density lipoprotein oxidation were all observed
This method ensures maximum bioavailability, meaning that a higher concentration of glutathione reaches the cells compared to oral supplements
However, given the possible high research costs to develop these compounds specifically for AILI, existing drugs with therapeutic potential in this hepatotoxicity model may be better choices