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Study drug was permanently discontinued due to an adverse event in 15.5% of semaglutide tablets-treated patients and 11.6% of placebo-treated patients

Semaglutide is a GLP-1 receptor medication that may help support appetite control, portion management, satiety, and long-term weight reduction alongside lifestyle changes and provider guidance

Participants on tirzepatide were also more likely to achieve weight reductions of 10%, 15%, 20%, and 25% compared to those on semaglutide

If you have a personal or family history of medullary thyroid carcinoma (MTC) or multiple endocrine neoplasia syndrome type 2 (MEN 2), tell your healthcare provider

Kidney Concerns: Some report worsening kidney issues, particularly if theyre prone to dehydration from the side effects