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GIP receptor agonism: Increases insulin sensitivity and contributes to body-weight control

Introduction Class B1 G-protein-coupled receptors (GPCRs) are activated by peptide hormones and neuropeptides that regulate essential physiological functions, including neuroprotection, bone turnover, cardiovascular tone, glycemic control, appetite, and energy balance (Bortolato et al., 2014)

GLP-1 is administered subcutaneously (just under the skin into the fat) using a very tiny needle

Tirzepatide Tirzepatide is a novel, synthetic peptide engineered to achieve dual agonism of both the glucose-dependent insulinotropic polypeptide (GIP) receptor and GLP-1

The GLP-1 fat loss treatment landscape includes options at various price points and potency levels