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1 One year after both the medication and their lifestyle support were stopped, average weight loss had fallen to 5.6%, while the placebo group sat at 0.1%

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Dopamine: If semaglutide reduces dopamine levels, it could lower motivation and make daily activities feel less rewarding

A 2026 review in Anais Brasileiros de Dermatologia found most local reactions are transient and resolve without dose adjustment

At NJ Primary Care, we take this into account and create a customized weight loss program which takes into account your unique needs, preferences, and medical considerations