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These findings support semaglutide's use in weight management when prescribed through appropriate medical supervision
Pre-existing risk factors : Individuals with established osteoporosis, previous fragility fractures, advanced age (particularly postmenopausal women), low baseline BMI, or those taking medications that affect bone metabolism (such as corticosteroids) may be more susceptible to bone density changes during weight loss
PMC 3480574
Wegovy injection initiates at 0.25 mg once weekly for four weeks and then follows a titration schedule every four weeks toward a maintenance dosage, with 2.4 mg the usual recommended maintenance dosage for weight reduction in adults and a labeled maximum of 7.2 mg once weekly for adults meeting the criteria in the label
Karsdal MA, Byrjalsen I, Henriksen K, Riis BJ, Christiansen C
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