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Chu et al showed that systemic levels of IGF-I can be restored by intravenous delivery of an AAV vector encoding mouse IGF-I(Eb) cDNA, in a streptozotocin (STZ)-induced mouse model of diabetic peripheral neuropathy

Efforts also should be directed toward developing formulations that enhance the bioavailability of GPS(Tong et al., 2023)

Conversely, the model group exhibited a significant elevation in immobility time, indicative of an insomnia-induced depressive-like state

Oxidative stress is damage caused by unstable molecules around us called free radicals, which are triggered by exposure to UV rays from the sun

Lancet Phase 2 trial in type 2 diabetes: Demonstrated clinically significant reductions in body weight and improved glycemic control, with a strong safety profile versus placebo and active comparators