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It mainly affects people of Mediterranean, South Asian, South-East Asian and Middle Eastern origin
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Henceforth, researchers devised numerous strategies for drug development, mainly by evading the enzymatic degradation of bioactive GLP-1 peptide by DPP-4
A study using a 15 N glycine stable isotope showed an anabolic protein turnover in HIV-only patients but no significant alterations in protein flux, degradation, or synthesis in TB-only and HIV/TB co-infected states (Paton et al., 2003), suggesting that HIV-related metabolic disruptions might be less pronounced in co-infected individuals