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Most users experience peak nausea within the first 12 weeks after starting or increasing their dose, with gradual improvement over the following 23 weeks as their body adjusts

Still cheaper ($265 CAD) in Canada and as the patent expires next year, likely to be less still

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Monitor for signs of acute gallbladder disease, such as cholelithiasis or cholecystitis

However, its important to avoid regular or long-term use without guidance, as some laxatives can lead to dependence and worsen constipation over time