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With retatrutide, the goal isn't replicating the weight loss seen in phase 2 trials

improved neurobehavioral outcomes

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Signs Your Liver May Need Attention Most people on GLP-1s experience no liver issues

There have been rare reports of issues related to the pancreas or gallbladder, though they were not very common in the early studies of retatrutide, and similar reports have been seen with all the other GLP-1 medications