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The results were notable: participants receiving the highest dose (12 mg) achieved a mean body weight reduction of approximately 24% , which is among the largest reductions observed in any pharmacological weight-loss trial to date

doi: 10.1038/s42255-024-01113-9 29 Pi-SunyerXAstrupAFujiokaKGreenwayFHalpernAKrempfMet al