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Thyroid 12:393-398, 2002

Reducing activity in the DMN can decrease rumination, which in turn can reduce pain and depressed feelings

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Furthermore, it has been suggested that melanotan 2 actually lowers the level of acetylcholine A carboxylase expression and even prevents the reduction of carnitine and palmitoyltransferase I mRNA in muscle-type tissues by pair-feeding in the muscles of obese rats