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92 However, clinicians should be aware that various gastrointestinal (e.g., perforated peptic ulcer, intestinal obstruction) and non-gastrointestinal conditions (e.g., renal insufficiency, macroamylasemia) can also cause mild elevations in pancreatic enzyme levels

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Heres what the clinical data shows: tirzepatide causes side effects in most people, particularly gastrointestinal issues like nausea, diarrhea, and constipation

Ahasan HM, Khan MAI, Mahbub S et al (2010) Melanosis colian atypical presentation

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