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However, peoples impairment lagged far behind, peaking about 5 hours after drinking alcohol even in participants well below the legal limit for driving under the influence (DUI)

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10.1016/j.pnmrs.2018.06.002 Prog

Elderly patients may be more sensitive to the medications effects and may require slower titration or lower maintenance doses, particularly if they have reduced renal function or are at higher risk for dehydration from gastrointestinal adverse effects

Pharmaceutical-grade: the USP product from makers like Pfizer/Hospira is the reference standard, but as an end user it usually means a prescription or a pharmacy, and bottle sizes often run larger than a research setup needs