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doi: 10.1007/s12975-011-0125-x

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Lancet Diabetes Endocrinol 2022;10:193206.ArticlePubMed 50

Mutation of a critical arginine in microsomal prostaglandin E synthase-1 shifts the isomerase activity to a reductase activity that converts prostaglandin H2 into prostaglandin F2alpha