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Studies show this early worsening happens in the first year or two, but then provides much better control of retinopathy long term

The combined study population is several thousand

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Farabegoli F, Papi A, Bartolini G, Ostan R, Orlandi M, 2010.(-)-Epigallocatechin-3-gallate downregulates Pg-P and BCRP in a tamoxifen resistant MCF-7 cell line