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Opioid System Involvement: May interact with opioid peptides, explaining analgesic effects [Sudakov 1987]

By directly addressing these neural and glial deficits, Cellular Therapy and Stem Cells for Insomnia aim to restore circadian balance and reestablish healthy sleep cycles [11-15]

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121 Mutations in the progranulin gene, GRN , which cause a genetic familial FTD, downregulate expression of EAAT2 astrocyte glutamate transporter, which mediates synaptic degeneration

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