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69 Therefore, these NAD + -dependent enzymes, namely, sirtuins, PARPs, and cADPRSs, are able to coregulate each other in competition for the same intracellular limiting NAD + pool

Differential metabolite abundance was assessed using linear models fitted separately for each metabolite (lm in R), with group as the predictor

Pharmacokinetics, pharmacodynamics, metabolism, toxicology and residues of phenylbutazone in humans and horses

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In contrast to saline-injected WT mice, saline-injected Gpx1 KO mice showed low GSH/GSSG ratio, increased hydrogen peroxide and high MDA level in the liver and spleen (Figure 6)