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Drug distribution predictors, BBB permeability and CNS permeability, suggest that the lead compounds can cross the BBB comparable to CQ ( In summary, we are reporting novel lead compounds with antiplasmodial activity which offer potential scaffolds for the development of antimalarial agents

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It seems that the lower SOD activity is partly a consequence of the increased oxidative and nitrative stress in the asthmatic airway and serves as a sensitive marker of airway redox and asthma severity [7]