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J Am Pharmacists Assoc 2023;63:1643-1645
The peptide activates the VEGFR2-Akt-eNOS signaling cascade, leading to increased vascular endothelial growth factor (VEGF) expression and subsequent vessel development
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Leptin also reduces the levels of orexin, which is another peptide located in the same region and like MCH, induces hunger [28]
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