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Significant differences among groups were analyzed using one-way analysis of variance (ANOVA) with Tukeys post hoc test or the KruskalWallis test with Dunns post hoc test

Potential Research Applications: Fat Metabolism: In obese animal models (e.g., Zucker rats), AOD 9604 reduced body weight gain by over 50% within 19 days (oral, 500 g/kg daily)

Some flavonoid compounds like quercetin and myricetin may also help manage blood pressure, while oleic acid may help lower blood pressure

The conversion of GSSG back to GSH during ROS production would explain the unbalanced activation of the glutathione oxidation/reduction cycle

227 In another randomized placebo-controlled trial, patients with high cholesterol took 80 mg of atorvastatin (Lipitor) (a common lipid-lowering medication that blocks cholesterol production) for four weeks and then added either 180 mg of bempedoic acid or placebo to their treatment regimen for four additional weeks