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10.1371/JOURNAL.PONE.0028668 57 FakhriS.PesceM.PatrunoA.MoradiS

Whereas the predominant irAEs with antiCTLA-4 are colitis and hypophysitis, treatment with an anti-PD1/PD-L1 can cause T1D, hypothyroidism, pneumonitis, and myocarditis, among others

Strategic recommendations: Develop nutrient-dense, portion-controlled products and messaging that highlights fullness and wellness rather than restriction

This dual mechanism not only makes it easier to adhere to a controlled diet but also helps prevent the common pitfalls of yo-yo dieting, such as binge eating following periods of restrictive eating