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A 2023 study published in the New England Journal of Medicine [1] found that Liraglutide, alongside lifestyle changes, resulted in significant weight loss (an average of 8.4%) compared to a placebo group

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Nevertheless, these therapies frequently have unfavorable impacts and fail to effectively address the metabolic issues linked to RA, such as oxidative stress and dyslipidemia 7

In addition, the GLP-1 enhancer sitagliptin exerts a protective role against diabetic cardiomyopathy via the GLP-1/PPAR pathway [36]

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